Bernardo Castello (or Castelli) (1557–1629) was an Italian painter of the late-Mannerist style, active mainly in Genoa and Liguria. He is mainly known as a portrait and historical painter. Bernardo Castello was born in Albaro, now a quarter of Genoa. He apprenticed under Andrea Semino and Luca Cambiaso, then he travelled through Italy, meeting other painters and creating his own particular style.
During his career he painted a lot of works and was very appreciated by famous poets, with which he had friendship relations. Among these he was a friend of Gabriello Chiabrera and Torquato Tasso, and took upon himself the task of designing the figures of the Jerusalem Delivered, published in 1590 (and also for a further edition, published in 1617). Some of these subjects were engraved by Agostino Carracci. Besides painting a number of works in Genoa, Castello was employed in Rome and worked also for the duke of Savoy Charles Emmanuel I.
Bernardo Castello died following a short illness in October, 1629, seventy-two years aged, while he was about to go to Rome, where he had been requested to paint a picture for St. Peter's Basilica. He was buried in the church of San Martino of Albaro.